Itraconazole Doesn't Have to Break the Bank

If you've looked at the price of Itraconazole without insurance, you might have had some sticker shock. Depending on the formulation, a month's supply can cost anywhere from $30 to over $900. That's a huge range — and the good news is that most patients can get their Itraconazole for far less than the sticker price.

Whether you're uninsured, underinsured, or just looking to lower your copay, this guide covers every major way to save money on Itraconazole in 2026.

How Much Does Itraconazole Cost Without Insurance?

Let's start with the cash prices you might see at the pharmacy counter:

• Generic Itraconazole capsules (100 mg, 30-count): $30–$150
• Sporanox brand capsules (100 mg, 30-count): $600–$900+
• Itraconazole oral solution (150 mL): $200–$500
• Tolsura capsules (65 mg, 28-count): $500–$800
• Onmel tablets (200 mg): Varies, typically $300–$600

Prices vary significantly between pharmacies. The same generic Itraconazole capsules that cost $150 at one pharmacy might be $35 at another just down the street. That's why comparison shopping matters.

Strategy 1: Use a Prescription Discount Card

Prescription discount cards are free to use and can dramatically reduce your out-of-pocket cost — sometimes even below your insurance copay. Here are the top options for Itraconazole:

GoodRx

GoodRx is the most widely known discount card. For generic Itraconazole 100 mg capsules (30-count), GoodRx prices typically range from $15 to $40 depending on the pharmacy. That's up to 80% off the cash price.

SingleCare

SingleCare offers similar savings. Prices for generic Itraconazole capsules are often in the $15–$35 range. SingleCare is accepted at most major pharmacies including CVS, Walgreens, and Walmart.

RxSaver

RxSaver compares prices across multiple discount programs and pharmacies. It can help you find the absolute lowest price in your area.

Other Discount Cards

Additional options include BuzzRx, Optum Perks, ScriptSave WellRx, America's Pharmacy, and CareCard. Prices vary by card and pharmacy, so it's worth checking multiple options.

Pro tip: Discount cards often work at independent pharmacies too — and independents sometimes have lower base prices than chains. Check prices at both chain and independent pharmacies in your area.

When to Use a Discount Card vs. Insurance

If your insurance copay for generic Itraconazole is higher than the discount card price (this happens more often than you'd think), you can use the discount card instead. Just tell the pharmacist you'd like to use the discount card rather than your insurance. You can't combine them, but you can choose whichever is cheaper.

Strategy 2: Ask for Generic Itraconazole

This is the single biggest money-saving move. Generic Itraconazole capsules cost $15–$40 with a discount card, compared to $600–$900+ for brand-name Sporanox. The active ingredient is identical.

If your prescription says "Sporanox" or another brand name, ask your doctor if they can change it to generic Itraconazole. In most cases, the generic is clinically equivalent for capsules. (Note: Tolsura uses a different formulation with enhanced absorption, so it's not a simple generic substitution.)

Strategy 3: Patient Assistance Programs

If you're uninsured or have financial hardship, patient assistance programs (PAPs) may provide Itraconazole for free or at very low cost:

NeedyMeds

NeedyMeds.org maintains a database of patient assistance programs. Search for Itraconazole to find programs offered by manufacturers and nonprofit organizations.

RxAssist

RxAssist.org is another comprehensive database of patient assistance programs. It includes both manufacturer programs and independent charitable programs.

RxHope

RxHope.com helps connect patients with manufacturer assistance programs. You can search by medication name and apply online.

Manufacturer Programs

For brand-name products:

• Tolsura: Mayne Pharma may offer copay assistance or patient support programs. Check tolsura.com for current offerings.
• Sporanox: As a largely genericized product, active savings programs are limited, but Janssen's patient assistance foundation may still cover qualifying patients.

State Programs

Many states have pharmaceutical assistance programs (SPAPs) that help residents afford medications. Eligibility varies by state, age, and income. Check with your state's health department or use the Medicare.gov tool to find programs in your area.

Strategy 4: Other Ways to Save

90-Day Supplies

If you're on a longer treatment course (common for onychomycosis or systemic mycoses), ask about a 90-day supply. The per-capsule cost is often lower, and you'll make fewer pharmacy trips. Mail-order pharmacies typically offer the best pricing on 90-day supplies.

Walmart $4 Program

Check Walmart's discount prescription list. While Itraconazole isn't always included, Walmart often has competitive pricing on generics.

Cost Plus Drugs

Mark Cuban's Cost Plus Drugs (costplusdrugs.com) offers transparent, low-cost pricing on many generic medications. Check whether Itraconazole is in their formulary — if so, prices are based on actual manufacturing cost plus a flat markup.

Compare Pharmacy Prices

Prices for the same generic Itraconazole can vary by $100+ between pharmacies. Always compare at least 3–4 pharmacies. Use GoodRx, SingleCare, or RxSaver to see prices across nearby pharmacies before you fill.

Ask About Pill Splitting (With Caution)

This does not apply to Itraconazole capsules — you should not split or open capsules. However, if your doctor prescribes a different antifungal that comes in scored tablets, pill splitting under medical guidance can sometimes reduce costs.

What About Insurance Coverage?

Most insurance plans cover generic Itraconazole capsules:

• Commercial insurance: Typically Tier 2 (preferred generic). Copays usually range from $5–$25.
• Medicare Part D: Generic Itraconazole is covered on most plans. Copays vary but are typically $5–$20 for preferred generics.
• Medicaid: Covered in most states with minimal or no copay.

Brand-name versions (Sporanox, Tolsura, Onmel) are often Tier 3 or higher and may require:

• Prior authorization: Your doctor needs to document why you need the brand instead of generic.
• Step therapy: You may need to try and fail on generic Itraconazole first.

If your insurance denies coverage, ask your doctor to submit an appeal with clinical justification.

Finding Itraconazole at the Best Price

Saving money only matters if you can actually find the medication. If you're having trouble locating Itraconazole, use Medfinder to check real-time pharmacy availability. For more tips, read our guides on finding Itraconazole in stock and checking pharmacy stock.

Final Thoughts

Nobody should skip their antifungal medication because of cost. With generic options as low as $15–$30 using discount cards, plus patient assistance programs for those who qualify, Itraconazole is accessible for most patients. Compare prices, use discount cards, ask for generics, and don't hesitate to explore assistance programs if you need help.

Start by searching for the best price at Medfinder, and take control of both your health and your budget.